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1

18F-PSMA-1007 PET/CT Detects Micrometastases in a Patient With Biochemically Recurrent Prostate Cancer

Giesel, Frederik L., Kesch, Claudia, Yun, Mijin, Cardinale, Jens, Haberkorn, Uwe, Kopka, Klaus, Kratochwil, Clemens, Hadaschik, Boris A.

Journal:

Clinical Genitourinary Cancer

Year:

2016

Language:

english

File:

PDF, 1.81 MB

english, 2016

2

Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7

Limpachayaporn, Panupun, Riemann, Burkhard, Kopka, Klaus, Schober, Otmar, Schäfers, Michael, Haufe, Günter

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

3

Synthesis of Geminal Difluorides by Oxidative Desulfurization−Difluorination of Alkyl Aryl Thioethers with Halonium Electrophiles in the Presence of Fluorinating Reagents and Its Application for 18 F-Radiolabeling

Hugenberg, Verena, Wagner, Stefan, Kopka, Klaus, Schober, Otmar, Schäfers, Michael, Haufe, Günter

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 987 KB

english, 2010

4

Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis

Waldmann, Christopher M., Hermann, Sven, Faust, Andreas, Riemann, Burkhard, Schober, Otmar, Schäfers, Michael, Haufe, Günter, Kopka, Klaus

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

5

Dosimetry for177Lu-DKFZ-PSMA-617: a new radiopharmaceutical for the treatment of metastatic prostate cancer

Delker, Andreas, Fendler, Wolfgang Peter, Kratochwil, Clemens, Brunegraf, Anika, Gosewisch, Astrid, Gildehaus, Franz Josef, Tritschler, Stefan, Stief, Christian Georg, Kopka, Klaus, Haberkorn, Uwe, Ba

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

6

18F-Labelled PSMA-1007 shows similarity in structure, biodistribution and tumour uptake to the theragnostic compound PSMA-617

Giesel, Frederik L., Cardinale, Jens, Schäfer, Martin, Neels, Oliver, Benešová, Martina, Mier, Walter, Haberkorn, Uwe, Kopka, Klaus, Kratochwil, Clemens

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2016

Language:

english

File:

PDF, 590 KB

english, 2016

7

68Ga-PSMA PET/CT: Joint EANM and SNMMI procedure guideline for prostate cancer imaging: version 1.0

Fendler, Wolfgang P., Eiber, Matthias, Beheshti, Mohsen, Bomanji, Jamshed, Ceci, Francesco, Cho, Steven, Giesel, Frederik, Haberkorn, Uwe, Hope, Thomas A., Kopka, Klaus, Krause, Bernd J., Mottaghy, Fe

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2017

Language:

english

File:

PDF, 472 KB

english, 2017

8

Effects of arm truncation on the appearance of the halo artifact in 68Ga-PSMA-11 (HBED-CC) PET/MRI

Afshar-Oromieh, Ali, Wolf, Maya, Haberkorn, Uwe, Kachelrieß, Marc, Gnirs, Regula, Kopka, Klaus, Schlemmer, Heinz-Peter, Freitag, Martin T.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2017

Language:

english

File:

PDF, 5.70 MB

english, 2017

9

Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5/P450 reductase null (HBRN) mice

Reed, Lindsay, Mrizova, Iveta, Barta, Frantisek, Indra, Radek, Moserova, Michaela, Kopka, Klaus, Schmeiser, Heinz H., Wolf, C. Roland, Henderson, Colin J., Stiborova, Marie, Phillips, David H., Arlt,

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

10

A Convenient Synthesis for HBED-CC-tris(tert-butyl ester)

Makarem, Ata, Konrad, Moritz, Liolios, Christos, Kopka, Klaus

Journal:

Year:

2018

Language:

english

File:

PDF, 349 KB

english, 2018

11

Current Status of PSMA-Radiotracers for Prostate Cancer: Data Analysis of Prospective Trials Listed on ClinicalTrials.gov

Zippel, Claus, Ronski, Sarah C., Bohnet-Joschko, Sabine, Giesel, Frederik L., Kopka, Klaus

Journal:

Pharmaceuticals

Year:

2020

Language:

english

File:

PDF, 1.26 MB

english, 2020

12

Radiofluorinated Pyrimidine-2,4,6-triones as Molecular Probes for Noninvasive MMP-Targeted Imaging

Hans-Jörg Breyholz, Stefan Wagner, Andreas Faust, Burkhard Riemann, Carsten Höltke, Sven Hermann, Otmar Schober, Michael Schäfers, Klaus Kopka

Journal:

Year:

2010

Language:

english

File:

PDF, 483 KB

english, 2010

13

Synthesis of an 18F-labelled high affinity β1-adrenoceptor PET radioligand based on ICI 89,406

Stefan Wagner, Marilyn P. Law, Burkhard Riemann, Victor W. Pike, Hans-Jörg Breyholz, Carsten Höltke, Andreas Faust, Christiane Renner, Otmar Schober, Michael Schäfers, Klaus Kopka

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 233 KB

english, 2006

14

Synthesis of (R)- and (S)-[O-methyl-11C]N-[2-[3-(2-cyano-phenoxy)-2-hydroxy-propylamino]-ethyl]-N′-(4-methoxy-phenyl)-urea as candidate high affinity β1-adrenoceptor PET radioligands

Stefan Wagner, Marilyn P. Law, Burkhard Riemann, Victor W. Pike, Hans-Jörg Breyholz, Carsten Höltke, Andreas Faust, Otmar Schober, Michael Schäfers, Klaus Kopka

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

15

A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: Radiosynthesis and initial small-animal PET studies

Stefan Wagner, Hans-Jörg Breyholz, Carsten Höltke, Andreas Faust, Otmar Schober, Michael Schäfers, Klaus Kopka

Journal:

Applied Radiation and Isotopes

Year:

2009

Language:

english

File:

PDF, 349 KB

english, 2009

16

The MMP inhibitor (R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-methylbutanamide: Improved precursor synthesis and fully automated radiosynthesis

Stefan Wagner, Andreas Faust, Hans-Jörg Breyholz, Otmar Schober, Michael Schäfers, Klaus Kopka

Journal:

Applied Radiation and Isotopes

Year:

2011

Language:

english

File:

PDF, 588 KB

english, 2011

17

Synthesis and first in vivo evaluation of new selective high affinity β1-adrenoceptor radioligands for SPECT based on ICI 89,406

Stefan Wagner, Klaus Kopka, Marilyn P. Law, Burkhard Riemann, Victor W. Pike, Otmar Schober, Michael Schäfers

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 611 KB

english, 2004

18

Synthesis, in vitro pharmacology and biodistribution studies of new PD 156707-derived ETA receptor radioligands

Carsten Höltke, Marilyn P. Law, Stefan Wagner, Hans-Jörg Breyholz, Klaus Kopka, Christoph Bremer, Bodo Levkau, Otmar Schober, Michael Schäfers

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 217 KB

english, 2006

19

PET-compatible endothelin receptor radioligands: Synthesis and first in vitro and in vivo studies

Carsten Höltke, Marilyn P. Law, Stefan Wagner, Klaus Kopka, Andreas Faust, Hans-Jörg Breyholz, Otmar Schober, Christoph Bremer, Burkhard Riemann, Michael Schäfers

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 986 KB

english, 2009

20

Characterization of 3-[123I]iodo-L-α-methyl tyrosine transport in astrocytes of neonatal rats

Klaus Kopka, Burkhard Riemann, Matthias Friedrich, Silke Winters, Hartmut Halfter, Matthias Weckesser, Florian Stögbauer, E. Bernd Ringelstein, Otmar Schober

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 520 KB

english, 2001

21

Kinetics of 3-[123I]iodo-l-α-methyltyrosine transport in rat C6 glioma cells

Burkhard Riemann, Florian Stögbauer, Klaus Kopka, Hartmut Halfter, Manuela Lasic, Anja Schirmacher, Torsten Kuwert, Matthias Weckesser, E. Bernd Ringelstein, Otmar Schober

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1999

Language:

english

File:

PDF, 67 KB

english, 1999

22

Early Effects of Irradiation on [123I]-IMT and [18F]-FDG Uptake in Rat C6 Glioma Cells

Burkhard Riemann, Stefan Könemann, Daniel Pöpping, Klaus Kopka, Matthias Weckesser, Normann Willich, Otmar Schober

Journal:

Strahlentherapie und Onkologie

Year:

2004

File:

PDF, 319 KB

2004

23

Targeting of matrix metalloproteinase activation for noninvasive detection of vulnerable atherosclerotic lesions

Dagmar Hartung, Michael Schäfers, Shinichiro Fujimoto, Bodo Levkau, Navneet Narula, Klaus Kopka, Renu Virmani, Chris Reutelingsperger, Leo Hofstra, Frank D. Kolodgie, Artiom Petrov, Jagat Narula

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 388 KB

english, 2007

24

Are [O-methyl-11C]derivatives of ICI 89,406 β1-adrenoceptor selective radioligands suitable for PET?

Marilyn P. Law, Stefan Wagner, Klaus Kopka, Victor W. Pike, Otmar Schober, Michael Schäfers

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2008

Language:

english

File:

PDF, 491 KB

english, 2008

25

Erratum to: Kinetics of 3-[123I]iodo-L-α-methyltyrosine transport in rat C6 glioma cells

Burkhard Riemann, Florian Stögbauer, Klaus Kopka, Hartmut Halfter, Manuela Lasic, Anja Schirmacher, Torsten Kuwert, Matthias Weckesser, Bernd E. Ringelstein, Otmar Schober

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2000

Language:

english

File:

PDF, 6 KB

english, 2000

26

Sequential scintigraphic strategy for the differentiation of brain tumours

Peter Matheja, Christian Rickert, Matthias Weckesser, Stefan Palkovic, Jan Löttgen, Burkhard Riemann, Klaus Kopka, Torsten Kuwert, Hansdetlef Wassmann, Werner Paulus, Otmar Schober

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2000

Language:

english

File:

PDF, 256 KB

english, 2000

27

18F-labelled cardiac PET tracers: selected probes for the molecular imaging of transporters, receptors and proteases

Klaus Kopka, Otmar Schober, Stefan Wagner

Journal:

Basic Research in Cardiology

Year:

2008

Language:

english

File:

PDF, 675 KB

english, 2008

28

Fluorinated isatin derivatives. Part 1: Synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors

Anil Kumar Podichetty, Andreas Faust, Klaus Kopka, Stefan Wagner, Otmar Schober, Michael Schäfers, Günter Haufe

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 329 KB

english, 2009

29

Design of new β1-selective adrenoceptor ligands as potential radioligands for in vivo imaging

Klaus Kopka, Stefan Wagner, Burkhard Riemann, Marilyn P. Law, Carsten Puke, Sajinder K. Luthra, Victor W. Pike, Thomas Wichter, Wilhelm Schmitz, Otmar Schober, Michael Schäfers

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 457 KB

english, 2003

30

5-Pyrrolidinylsulfonyl Isatins as a Potential Tool for the Molecular Imaging of Caspases in Apoptosis

Kopka, Klaus, Faust, Andreas, Keul, Petra, Wagner, Stefan, Breyholz, Hans-Jörg, Höltke, Carsten, Schober, Otmar, Schäfers, Michael, Levkau, Bodo

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 340 KB

english, 2006

31

Molecular cardiovascular imaging using scintigraphic methods

Lars Stegger, Klaus Schäfers, Klaus Kopka, Stefan Wagner, Sven Hermann, Peter Kies, Marilyn Law, Otmar Schober, Michael Schäfers

Journal:

European Radiology

Year:

2007

Language:

english

File:

PDF, 420 KB

english, 2007

32

Genetic and genomic analysis of legume flowers and seeds

Claire Domoney, Gérard Duc, TH Noel Ellis, Cristina Ferrándiz, Christian Firnhaber, Karine Gallardo, Julie Hofer, Joachim Kopka, Helge Küster, Franciso Madueño, Nathalie G Munier-Jolain, Klaus Mayer,

Journal:

Current Opinion in Plant Biology

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

33

Radiosynthesis of a 68Ga labeled matrix metalloproteinase inhibitor as a potential probe for PET imaging

Michael Claesener, Otmar Schober, Stefan Wagner, Klaus Kopka

Journal:

Applied Radiation and Isotopes

Year:

2012

Language:

english

File:

PDF, 479 KB

english, 2012

34

Maintenance of real objects and their verbal designations in working memory

Stefan Kaiser, Marie-Luise Kopka, Mirjam Rentrop, Stephan Walther, Klaus Kronmüller, Robert Olbrich, Matthias Weisbrod, Christoph Stippich

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

35

Synthesis and preliminary biological evaluation of new radioiodinated MMP inhibitors for imaging MMP activity in vivo

Klaus Kopka, Hans-Jörg Breyholz, Stefan Wagner, Marilyn P. Law, Burkhard Riemann, Sandra Schröer, Monika Trub, Benedicte Guilbert, Bodo Levkau, Otmar Schober, Michael Schäfers

Journal:

Nuclear Medicine and Biology

Year:

2004

Language:

english

File:

PDF, 225 KB

english, 2004

36

Preclinical evaluation of an 18F-labelled β1-adrenoceptor selective radioligand based on ICI 89,406

Marilyn P. Law, Stefan Wagner, Klaus Kopka, Christiane Renner, Victor W. Pike, Otmar Schober, Michael Schäfers

Journal:

Nuclear Medicine and Biology

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

37

Characterization of 3-[123I]iodo-L-α-methyl tyrosine ([123I]IMT) transport into human Ewing’s sarcoma cells in vitro

Christiane Franzius, Klaus Kopka, Frans van Valen, Vera Eckervogt, Burkhard Riemann, Joachim Sciuk, Otmar Schober

Journal:

Nuclear Medicine and Biology

Year:

2001

Language:

english

File:

PDF, 204 KB

english, 2001

38

Kinetic parameters of 3-[123I]iodo-L-α-methyl tyrosine ([123I]IMT) transport in human GOS3 glioma cells

Burkhard Riemanna, Klaus Kopka, Florian Stögbauer, Hartmut Halfter, Sonja Ketteler, T.Q.Vu Phan, Christiane Franzius, Matthias Weckesser, E. Bernd Ringelstein, Otmar Schober

Journal:

Nuclear Medicine and Biology

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

39

3-[123I]Iodo-L-α-methyl tyrosine transport into human fibroblasts and comparison with Ewing’s sarcoma cells

Christiane Franzius, Klaus Kopka, Frans van Valen, Burkhard Riemann, Joachim Sciuk, Otmar Schober

Journal:

Nuclear Medicine and Biology

Year:

2002

Language:

english

File:

PDF, 136 KB

english, 2002

40

Fluorine and Health || 18F‐Labeled PET‐Tracers for Cardiological Imaging

Year:

2008

Language:

english

File:

PDF, 1024 KB

english, 2008

41

Efficient synthesis of a fluorine-18 labeled biotin derivative

Michael Claesener, Hans-Jörg Breyholz, Sven Hermann, Andreas Faust, Stefan Wagner, Otmar Schober, Michael Schäfers, Klaus Kopka

Journal:

Nuclear Medicine and Biology

Year:

2012

Language:

english

File:

PDF, 550 KB

english, 2012

42

Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents

Limpachayaporn, Panupun, Schäfers, Michael, Schober, Otmar, Kopka, Klaus, Haufe, Günter

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.87 MB

english, 2013

43

Fluorinated Isatin Derivatives. Part 2. New N -Substituted 5-Pyrrolidinylsulfonyl Isatins as Potential Tools for Molecular Imaging of Caspases in Apoptosis

Podichetty, Anil K., Wagner, Stefan, Schröer, Sandra, Faust, Andreas, Schäfers, Michael, Schober, Otmar, Kopka, Klaus, Haufe, Günter

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 225 KB

english, 2009

44

Synthesis, 18 F-Radiolabeling, and in Vivo Biodistribution Studies of N -Fluorohydroxybutyl Isatin Sulfonamides using Positron Emission Tomography

Limpachayaporn, Panupun, Wagner, Stefan, Kopka, Klaus, Hermann, Sven, Schäfers, Michael, Haufe, Günter

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 3.61 MB

english, 2013

45

A Closer Look at the Bromine–Lithium Exchange with tert -Butyllithium in an Aryl Sulfonamide Synthesis

Waldmann, Christopher, Schober, Otmar, Haufe, Günter, Kopka, Klaus

Journal:

Organic Letters

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

46

A New Generation of Radiofluorinated Pyrimidine-2,4,6-triones as MMP-Targeted Radiotracers for Positron Emission Tomography

Schrigten, Daniela, Breyholz, Hans-Jörg, Wagner, Stefan, Hermann, Sven, Schober, Otmar, Schäfers, Michael, Haufe, Günter, Kopka, Klaus

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

47

C-5-Disubstituted Barbiturates as Potential Molecular Probes for Noninvasive Matrix Metalloproteinase Imaging

Breyholz, Hans-Jörg, Schäfers, Michael, Wagner, Stefan, Höltke, Carsten, Faust, Andreas, Rabeneck, Helmut, Levkau, Bodo, Schober, Otmar, Kopka, Klaus

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 156 KB

english, 2005

48

Fluorinated isatin derivatives. Part 3. New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors

Podichetty, Anil Kumar, Wagner, Stefan, Faust, Andreas, Schäfers, Michael, Schober, Otmar, Kopka, Klaus, Haufe, Günter

Journal:

Future Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

49

Radiation dosimetry and first therapy results with a124I/131I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy

Zechmann, Christian M., Afshar-Oromieh, Ali, Armor, Tom, Stubbs, James B., Mier, Walter, Hadaschik, Boris, Joyal, John, Kopka, Klaus, Debus, Jürgen, Babich, John W., Haberkorn, Uwe

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

50

PET/CT studies of multiple myeloma using18 F-FDG and18 F-NaF: comparison of distribution patterns and tracers’ pharmacokinetics

Sachpekidis, Christos, Goldschmidt, Hartmut, Hose, Dirk, Pan, Leyun, Cheng, Caixia, Kopka, Klaus, Haberkorn, Uwe, Dimitrakopoulou-Strauss, Antonia

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2014

Language:

english

File:

PDF, 484 KB

english, 2014

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